Cost Analysis of Cold Plasma for Wound Care Among Patients with Type 2 Diabetes Mellitus in Thai Community Hospitals

Authors

  • Utoomporn Wongsin 1 Department of Public Health Administration, Faculty of Public Health, Mahidol University, Thailand.
  • Kwanpracha Chiangchaisakulthai Health Academic Bureau, Ministry of Public Health, Thailand.
  • Passakorn Suanrueang Department of Health Education and Behavioral Sciences., Faculty of Public Health, Mahidol University, Thailand.
  • Patchanee Thumwanna Foundation for Research Institute on Social Protection and Health (FRoSPaH), Nonthaburi, Thailand
  • Nutnitima Changprajuck Foundation for Research Institute on Social Protection and Health (FRoSPaH), Nonthaburi, Thailand

Keywords:

Cost analysis, Cold Bio Plasma, Wound Care, Diabetes Mellitus, Community hospitals

Abstract

This study estimated unit cost of cold plasma wound care for Type 2 Diabetes Mellitus (T2DM) patients in Thai community hospitals. Utilizing a retrospective cross-sectional design, we analyzed 2025 cost data from four representative facilities from the provider’s perspective. The hospital cost information consisted of wound care service data, hospital statistics, and cost information. We used the codes from the 10th revision of the International Classification of Diseases (ICD-10) to identify diagnosis code of T2DM. Applied Activity-Based Costing: ABC were used to estimate average cost per visit and cost per person.

The results indicated that labor cost was the majority of total cost, while material and capital costs varied between hospitals. The unit cost of wound care using cold plasma per visit for patients with T2DM in 2025 was between THB 519 and THB 939. The unit cost of wound care using plasma per person for patients with T2DM was between THB 4,436 and THB 9,176.  Considering in each hospital, Hospital C reported the highest total cost (THB939), followed by Hospital A (THB 794), Hospital B (THB 676), and Hospital D (THB 519). Our cost analysis was based on real-world cost data, offering valuable insights to support budgeting and resource management for cold plasma wound care among patients with T2DM at community hospitals.

References

Abu Rached, N., Kley, S., Storck, M., Meyer, T., & Stücker, M. (2023). Cold Plasma Therapy in Chronic Wounds—A Multicenter, Randomized Controlled Clinical Trial (Plasma on Chronic Wounds for Epidermal Regeneration Study): Preliminary Results. Journal of Clinical Medicine, 12(15), 5121. https://doi.org/10.3390/jcm12155121

Armstrong, D. G., Boulton, A. J. M., & Bus, S. A. (2017). Diabetic Foot Ulcers and Their Recurrence. New England Journal of Medicine, 376(24), 2367–2375. https://doi.org/10.1056/NEJMra1615439

Arruzzoli, S., Leoni, O., Buffoli, M., & Capolongo, S. (2025). Comparative cross national analysis of healthcare service provision in community health centers based on policies and regulations from 13 international models. Discover Health Systems, 4(1), 119. https://doi.org/10.1007/s44250-025-00292-w

Aujirapongpan, S., Meesuk, K., Theinsathid, P., & Maneechot, C. (2020). Performance Evaluation of Community Hospitals in Thailand: An Analysis Based on the Balanced Scorecard Concept. Iranian Journal of Public Health, 49(5), 906–913.

Bhatt, P., Reema, & Sankaranarayanan, K. (2025). Cold Atmospheric Plasma as a Promising Medical Device for Wound Healing: Implications from Protein Perspective. Regenerative Engineering and Translational Medicine. https://doi.org/10.1007/s40883-025-00410-3

Braný, D., Dvorská, D., Halašová, E., & Škovierová, H. (2020). Cold Atmospheric Plasma: A Powerful Tool for Modern Medicine. International Journal of Molecular Sciences, 21(8), Article 8. https://doi.org/10.3390/ijms21082932

Cold plasma against chronic wounds—Www.max-planck-innovation.com. (2023). https://www.max-planck-innovation.com/max-planck-innovation/news/press-releases/press-release/cold-plasma-against-chronic-wounds.html

Cooper, R., & Kaplan, R. S. (1992). Activity-Based Systems: Measuring the Costs of Resource Usage. 15.

Diabetes Association of Thailand under The Patronage of Her Royal Highness Princess Maha Chakri Sirindhorn. (2026). Clinical Practice Guideline for Diabetes 2023. https://www.dmthai.org/new/index.php/sara-khwam-ru/sahrab-bukhkhl-thawpi/diabetes-book/naewthang-wech-ptibati-sahrab-rokh-bea-hwan-2566

Díaz-Herrera, M. Á., González-Durán, M., Rodríguez-Martínez, F. J., Tujillo-Flores, G., Tuset-Mateu, N., Verdú-Soriano, J., Gea-Caballero, V., Sanllorente-Melenchón, A., Almeda-Ortega, J., Cunillera-Puértolas, O., Acedo-Anta, M., & Martínez-Riera, J. R. (2025). The financial burden of chronic wounds in primary care: A real-world data analysis on cost and prevalence. International Journal of Nursing Studies Advances, 8, 100313. https://doi.org/10.1016/j.ijnsa.2025.100313

Dubey, S. K., Parab, S., Alexander, A., Agrawal, M., Achalla, V. P. K., Pal, U. N., Pandey, M. M., & Kesharwani, P. (2022). Cold atmospheric plasma therapy in wound healing. Process Biochemistry, 112, 112–123. https://doi.org/10.1016/j.procbio.2021.11.017

Edmonds, M., Manu, C., & Vas, P. (2021). The current burden of diabetic foot disease. Journal of Clinical Orthopaedics and Trauma, 17, 88–93. https://doi.org/10.1016/j.jcot.2021.01.017

Eriksson, E., Liu, P. Y., Schultz, G. S., Martins-Green, M. M., Tanaka, R., Weir, D., Gould, L. J., Armstrong, D. G., Gibbons, G. W., Wolcott, R., Olutoye, O. O., Kirsner, R. S., & Gurtner, G. C. (2022). Chronic wounds: Treatment consensus. Wound Repair and Regeneration, 30(2), 156–171. https://doi.org/10.1111/wrr.12994

Frykberg, R. G., & Banks, J. (2015). Challenges in the Treatment of Chronic Wounds. Advances in Wound Care, 4(9), 560–582. https://doi.org/10.1089/wound.2015.0635

International Diabetes Federation. (2025). IDF Diabetes Atlas 2025. Diabetes Atlas. https://diabetesatlas.org/resources/idf-diabetes-atlas-2025/

Kitreerawutiwong, N., Jordan, S., & Hughes, D. (2017). Facility type and primary care performance in sub-district health promotion hospitals in Northern Thailand. PLOS ONE, 12(3), e0174055. https://doi.org/10.1371/journal.pone.0174055

Kunsathian, J., Pimolkatekul, S., & Wongchan, N. (2025). Diabetes Patients Follow-up Tracking System in Urban Community: A Case Study of the Diabetes Center, Charoenkrung Pracharak Hospital. Journal of The Royal Thai Army Nurses, 26(3), 19–26.

Ministry of Finance,Thailand. (2021). Depreciation and Amortization information. https://www.cgd.go.th/cs/internet/internet/edas.html?page_locale=en_US

Puangpet, T., Pongkunakorn, T., Chulkarat, N., Bunlangjit, C., Surawit, A., Pinsawas, B., Mongkolsucharitkul, P., & Mayurasakorn, K. (2022). Control and complications of diabetes in urban primary care units in Thailand: A cross-sectional study. BMC Primary Care, 23(1), 212. https://doi.org/10.1186/s12875-022-01823-7

Sun, H., Saeedi, P., Karuranga, S., Pinkepank, M., Ogurtsova, K., Duncan, B. B., Stein, C., Basit, A., Chan, J. C. N., Mbanya, J. C., Pavkov, M. E., Ramachandaran, A., Wild, S. H., James, S., Herman, W. H., Zhang, P., Bommer, C., Kuo, S., Boyko, E. J., & Magliano, D. J. (2022). IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Research and Clinical Practice, 183, 109119. https://doi.org/10.1016/j.diabres.2021.109119

Supasit Pannarunothai, Nilawan Yoopukdee, Piyameth Dilokthornsakul, Nattanun Wetsasuntorn, Nattasit Chuchote, Pantip Khamta, & Parunee Yimsabai. (2022). Cost-effectiveness study of chronic wound treatment with Low Temperature Atmospheric Pressure Plasma versus Standard Care in public hospitals. (pp. 1–62). Center for Health Equity Monitoring Foundation.

Tonaree, W., Taweepraditpol, S., Kongkunnavat, N., Poungjantaradej, N., Kotistienkul, B., Yongsuvimol, M., Chinaroonchai, K., Rachata, P., Ongkasuwan, P., Chansanti, O., Mongkornwong, A., Chaichote, C., & Chuangsuwanich, A. (2025). The Efficacy of Low-Temperature Atmospheric-Pressure Plasma (LTAPP) in the Multicenter Treatment of Pressure Ulcers: A Randomized Controlled Trial. The International Journal of Lower Extremity Wounds, 15347346251323940. https://doi.org/10.1177/15347346251323940

Utoomporn Wongsin, Passakorn Suanrueang, & Tuo-Yu Chen. (2023). Cost Analysis of Outpatient Services for Hypertension, Heart Attack, and Stroke among Older Adults in Community Hospitals in Thailand. Journal of Health Systems Research, 17(2), 317–328.

Witvorapong, N., Ngamkiatphaisan, S., & Sriratanaban, J. (2022). Cost analysis of a teaching hospital in Thailand: Impacts of the first wave of COVID-19. PLOS ONE, 17(9), e0273771. https://doi.org/10.1371/journal.pone.0273771

World Health Organization. (2019). ICD-10 Version:2019. https://icd.who.int/browse10/2019/en

Yousefian, F., Hesari, R., Jensen, T., Obagi, S., Rgeai, A., Damiani, G., Bunick, C. G., & Grada, A. (2023). Antimicrobial Wound Dressings: A Concise Review for Clinicians. Antibiotics, 12(9), 1434. https://doi.org/10.3390/antibiotics12091434

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Published

2026-04-24

How to Cite

Wongsin, U., Chiangchaisakulthai, K. ., Suanrueang, P., Thumwanna, P. ., & Changprajuck, N. . (2026). Cost Analysis of Cold Plasma for Wound Care Among Patients with Type 2 Diabetes Mellitus in Thai Community Hospitals. Journal of Health Policy, Law and Administration, 12(2), 289–297. retrieved from https://so05.tci-thaijo.org/index.php/journal_law/article/view/288576

Issue

Vol. 12 No. 2 (2026): May-August

Section

Original Article

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